Cloud labs executing model-written protocols
Statement (NASA form)
Given that remote wet labs accept protocol files and run them with less human judgment than a PI, there is a possibility of a model-authored protocol executing on rented robotics resulting in physical biological work without a responsible scientist in the loop.
The lab does not know if the customer understands what they ordered.
Composite 13 = 2×5 + 3
Applicable mitigations
Controls · Mandatory, model-aware synthesis screening · Restore independent biosecurity staff at frontier labs · Know-your-customer for high-risk biological queries · Treaty limit on fully autonomous targeting · Meaningful human control with a reconstructable why · Adversarial test sets built from civilian lookalikes · Model Hardware Standard with safety limits on physical agents